Roger D. Sloboda
Appointments
Ira Allen Eastman Professor of Biological Sciences, Emeritus
Professor in the Molecular and Cellular Biology Program, Emeritus
Area of Expertise
Cell biology,
Biochemistry
Biography
Cilia and flagella, which project from the cell surface of many different cell types, are involved in cell motility. They also act like antenna and sense environmental conditions. They are taken apart at each cell division and reassembled by the two, newly formed daughter cells. Our lab is studying the steps required for the disassembly of cilia and flagella to occur prior to the start of cell division.
Education
B.S., State University of New York at Albany
Ph.D., Rensselaer Polytechnic Institute
Publications
Bloodgood, Robert A., Joseph Tetreault, and Roger D Sloboda. (2019). The Chlamydomonas flagellar membrane glycoprotein FMG-1B is necessary for expression of force at the flagellar surface. Journal of Cell Science, 132, jcs233429. doi:10.1242/jcs.233429
First Person – Robert Bloodgood and Roger Sloboda. (2019). Journal of Cell Science 132, jcs237461. doi:10.1242/jcs.23746
Mizuno, Katsutoshi and Sloboda, Roger D. (2017). Protein arginine methyltransferases interact with intraflagellar transport particles and change location during flagellar growth and resorption. Molecular Biology of the Cell, 28(9):1208-1222. doi: 10.1091/mbc.E16-11-0774. PMID: 28298486
Sloboda, Roger D. (2016). Purification and Localization of Intraflagellar Transport Particles and Polypeptides, in: Cytoskeleton; Methods and Protocols, 3rd ed., pp. 119-137. doi 10.1007/978-1-4939-3124-8_6
Sloboda, Roger D. (2015). Isolation and Analysis of Microtubules and Associated Proteins, In: Subcellular Fractionation: A Laboratory Manual, edited by Paul R. Pryor, Cold Spring Harbor Press, New York, pp: 115-140. doi: 10.1101/pdb.top074526
Kull, F. Jon and Roger D. Sloboda (2014). A Slow Dance for Microtubule Acetylation. Cell, 157:1255-1256. doi: 10.1016/j.cell.2014.05.021
Werner-Petersen, Rita and Sloboda, Roger D. (2013). Methylation of Structural Components of the Axoneme Occurs During Flagellar Disassembly, Biochemistry, 52:8501-09. doi 10.1021/bi4011623
Sloboda, Roger D. (2009). Flagella and Cilia: The Long and the Short of It. Current Biology, 19:R1084-1087. doi 10.1016/j.cell.2014.05.021
Sloboda, Roger D. (2009). Post-Translational Protein Modifications in Cilia and Flagella. Methods in Cell Biology, 94:347-363. doi:10.1016/S0091-679X(08)94018-8
Sloboda, Roger D. (2009). Purification and Localization of Intraflagellar Transport Particles and Polypeptides, in Methods in Molecular Biology: Cytoskeleton Methods and Protocols, ed. by Ray Gavin, Humana Press, 586:207-225. doi: 10.1007/978-1-4939-3124-8_6
Sloboda, Roger D. and Louisa Howard (2009). Protein Methylation in Full Length Chlamydomonas Flagella. Cell Motility and the Cytoskeleton, 66:650-660. doi: 10.1002/cm.20387
Schneider, Mark J., Megan Ulland, and Roger D. Sloboda (2008). A Protein Methylation Pathway in Chlamydomonas Flagella Is Active During Flagellar Resorption, Molecular Biology of the Cell, 19:4319-4327. doi: 10.1091/mbc.E08-05-0470
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